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Hong Seok Choi Selected Research

Neoplastic Cell Transformation

10/2018SUV39H1/DNMT3A-dependent methylation of the RB1 promoter stimulates PIN1 expression and melanoma development.
10/2013The prolyl isomerase Pin1 interacts with and downregulates the activity of AMPK leading to induction of tumorigenicity of hepatocarcinoma cells.
1/2013Inhibitory effects of a new 1H-pyrrolo[3,2-c]pyridine derivative, KIST101029, on activator protein-1 activity and neoplastic cell transformation induced by insulin-like growth factor-1.
12/20115'-Nitro-indirubinoxime inhibits epidermal growth factor- and phorbol ester-induced AP-1 activity and cell transformation through inhibition of phosphorylation of Pin1.
3/2010The prolyl isomerase Pin1 enhances HER-2 expression and cellular transformation via its interaction with mitogen-activated protein kinase/extracellular signal-regulated kinase kinase 1.
4/2009The prolyl isomerase Pin1 interacts with a ribosomal protein S6 kinase to enhance insulin-induced AP-1 activity and cellular transformation.
8/2008Fucoidan from Laminaria cichorioides inhibits AP-1 transactivation and cell transformation in the mouse epidermal JB6 cells.
5/2008Inhibitory effects of fucoidan on activation of epidermal growth factor receptor and cell transformation in JB6 Cl41 cells.
1/2008Cot, a novel kinase of histone H3, induces cellular transformation through up-regulation of c-fos transcriptional activity.
7/2005Phosphorylation of histone H3 at serine 10 is indispensable for neoplastic cell transformation.
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Hong Seok Choi Research Topics

Disease

30Neoplasms (Cancer)
12/2021 - 06/2004
17Breast Neoplasms (Breast Cancer)
03/2021 - 09/2006
17Carcinogenesis
03/2021 - 06/2004
12Melanoma (Melanoma, Malignant)
06/2022 - 08/2005
11Neoplastic Cell Transformation
10/2018 - 06/2004
4Colonic Neoplasms (Colon Cancer)
05/2015 - 03/2010
3Fibrosarcoma
09/2020 - 06/2004
3Hepatocellular Carcinoma (Hepatoma)
01/2016 - 08/2002
3Infections
03/2015 - 01/2012
3Hypoxia (Hypoxemia)
11/2010 - 05/2008
2Obesity
07/2014 - 10/2008
2Stomach Neoplasms (Stomach Cancer)
06/2014 - 02/2014
2Skin Neoplasms (Skin Cancer)
04/2009 - 08/2005
1Botulism
02/2022
1Anthrax
02/2022
1Facial Asymmetry
12/2020
1Triple Negative Breast Neoplasms
09/2020
1Cataract (Cataracts)
12/2019
1Anophthalmos (Anophthalmia)
12/2019
1Glaucoma
12/2019
1Eye Diseases (Eye Disease)
12/2019
1Microphthalmos
12/2019
1Cleft Lip (Harelip)
09/2019
1Dentofacial Deformities
09/2019
1Granuloma
12/2018
1Alzheimer Disease (Alzheimer's Disease)
12/2018
1Dyspnea (Shortness of Breath)
12/2018
1Retinoblastoma (Glioblastoma, Retinal)
10/2018
1Pseudopseudohypoparathyroidism
06/2018
1Brachydactyly
06/2018
1Ischemia
01/2018
1Liver Failure
01/2018
1Body Weight (Weight, Body)
01/2017
1Creutzfeldt-Jakob Syndrome (Creutzfeldt-Jakob Disease)
01/2016
1Prion Diseases (Transmissible Spongiform Encephalopathies)
01/2016
1Inflammation (Inflammations)
01/2016
1Fibrosis (Cirrhosis)
01/2016

Drug/Important Bio-Agent (IBA)

9Phosphotransferases (Kinase)IBA
06/2022 - 06/2004
9Peptidylprolyl Isomerase (Prolyl Isomerase)IBA
02/2019 - 05/2008
8Proteins (Proteins, Gene)FDA Link
10/2018 - 06/2004
7Transcription Factor AP-1 (Transcription Factor AP 1)IBA
12/2016 - 08/2005
7Epidermal Growth Factor (EGF)IBA
10/2013 - 07/2005
5Pharmaceutical PreparationsIBA
12/2016 - 09/2006
5TamoxifenFDA LinkGeneric
02/2015 - 08/2009
3Mitogen-Activated Protein Kinase Kinases (MEKs)IBA
06/2022 - 10/2008
3VemurafenibIBA
06/2022 - 12/2019
3jugloneIBA
03/2021 - 03/2010
3Histones (Histone)IBA
10/2018 - 07/2005
3AMP-Activated Protein KinasesIBA
01/2017 - 01/2011
3Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
11/2010 - 05/2008
2Extracellular Signal-Regulated MAP Kinases (Extracellular Signal Regulated Kinases)IBA
06/2022 - 06/2014
2Biological ProductsIBA
02/2022 - 05/2008
2VaccinesIBA
02/2022 - 01/2012
2MethyltransferasesIBA
12/2021 - 10/2018
2Peptides (Polypeptides)IBA
12/2018 - 01/2012
2Glucose (Dextrose)FDA LinkGeneric
01/2017 - 09/2006
2Sorafenib (BAY 43-9006)FDA Link
05/2015 - 01/2013
2Rituximab (Mabthera)FDA Link
03/2015 - 12/2013
2JNK Mitogen-Activated Protein KinasesIBA
06/2014 - 04/2009
2Insulin (Novolin)FDA Link
01/2013 - 04/2009
2epigallocatechin gallate (epigallocatechin-3-gallate)IBA
06/2010 - 10/2008
2TeaIBA
06/2010 - 10/2008
2CaspasesIBA
10/2008 - 09/2006
2fucoidanIBA
08/2008 - 05/2008
2Small Interfering RNA (siRNA)IBA
05/2008 - 06/2004
1Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA
06/2022
1DNA VaccinesIBA
02/2022
1Biological Warfare AgentsIBA
02/2022
1N-methyladenosineIBA
12/2021
16-methyladenineIBA
12/2021
1Serine-Threonine Kinase 3IBA
01/2021
1ThiazolesIBA
01/2021
1UbiquitinIBA
01/2021
1OxazolesIBA
09/2020
15'- O- (9- phenylxanthen- 9- yl)- 2'- deoxynebularineIBA
12/2019
1Tretinoin (Retinoic Acid)FDA LinkGeneric
12/2019
1Proline (L-Proline)FDA Link
02/2019
1EnzymesIBA
02/2019
1Amyloid beta-PeptidesIBA
12/2018
1DNA Methyltransferase 3AIBA
10/2018
1ChromatinIBA
10/2018
1Messenger RNA (mRNA)IBA
10/2018
15-phenylpent-4-enyl-1-hydroperoxideIBA
06/2018
1Parathyroid Hormone (Parathormone)IBA
06/2018
1ElectrolytesIBA
06/2018
1salicylhydroxamic acid (SHAM)IBA
01/2018
1AntioxidantsIBA
01/2018
1NADP (NADPH)IBA
01/2018
1raf KinasesIBA
12/2016
1Biomarkers (Surrogate Marker)IBA
01/2016
114-3-3 Proteins (14-3-3 Protein)IBA
01/2016
11-phenyl-3,3-dimethyltriazene (PDT)IBA
08/2015
1Prednisolone (Predate)FDA LinkGeneric
03/2015

Therapy/Procedure

6Therapeutics
12/2016 - 07/2010
3Drug Therapy (Chemotherapy)
12/2021 - 03/2015
2Orthognathic Surgery
09/2019 - 12/2018
1Orthognathic Surgical Procedures
12/2020
1Oral Surgery (Maxillofacial Surgery)
09/2019
1Radiofrequency Ablation
01/2016
1Photochemotherapy (Photodynamic Therapy)
08/2015